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A brief review on heterocyclic compounds with promising antifungal activity against Candida species

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dc.contributor.author Korol, Nataliya
dc.contributor.author Molnar-Babilya, Dzhosiya
dc.contributor.author Молнар-Бабіля, Джосія Імреївна
dc.contributor.author Slivka, Mikhailo
dc.contributor.author Onysko, Mikhajlo
dc.date.accessioned 2023-02-20T07:42:34Z
dc.date.available 2023-02-20T07:42:34Z
dc.date.issued 2022
dc.identifier.uri http://dspace.msu.edu.ua:8080/jspui/handle/123456789/9535
dc.description A brief review on heterocyclic compounds with promising antifungal activity against Candida species / Nataliya Korol, Dzhosiya Molnar-Babilya, Mikhailo Slivka, Mikhajlo Onysko // Korol et al., Organic Communications (2022) 15:4. - Р. 304-323 uk_UA
dc.description.abstract The most common reason for fungal infections is the development of Candida yeasts. Candida naturally is occurs on the skin and on most mucosal surfaces. It is proven that 90% of infections are caused by five Candida species: Candida albicans, Candida glabrata, Candida tropicalis, Candida parapsilosis, and Candida krusei. Herein we’ve reviewed isolated and fused heterocyclic compounds that exhibit antifungal activity against Candida strains. Over 200 potential fungicidal agents were described, and some of the particularities which affect the action values were determined. Thus, it was noted that the presence of nitro-, methoxy-, trifluoromethyl-, and/or halogenocontaining groups at the specific positions in the benzene ring could significantly increase the inhibition of yeasts growth. That’s why using these patterns together with heterocycles while designing target compounds could speed up the search for new antifungal drugs. uk_UA
dc.language.iso other uk_UA
dc.subject heterocyclic compounds uk_UA
dc.subject fungicidal drugs uk_UA
dc.subject гетероциклічні сполуки uk_UA
dc.subject фунгіцидні препарати uk_UA
dc.title A brief review on heterocyclic compounds with promising antifungal activity against Candida species uk_UA
dc.type Article uk_UA


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